$109.00
Epithalon is a synthetic tetrapeptide studied for its potential role in cellular ageing, telomere regulation, and biological longevity. It has been studied for its potential role in telomerase activity, telomere length regulation, sleep-related pathways, immune response, and oxidative stress. With a strong history of research in Russia and Europe, Epithalon is investigated for its potential in delaying biological ageing and improving overall life span.
18 in stock
This product contains the well-known epithalon peptide, which is commonly studied for its potential role in cellular health and longevity.
This peptide is made up of Alanine-Glutamic acid-Aspartic acid-Glycine (Ala-Glu-Asp-Gly or AEDG).
It is in a lyophilised form, which is a freeze-dried white powder, and it is in a straight polypeptide chain.
In recent research, it has been confirmed that in normal human somatic cells that go through the cellular ageing process, this epithalon enhances their telomerase activity and produces an increase in telomere length.
Studies suggest that this epithalon acts on some of the cancer cells by the mechanism of ALT instead of telomerase, which is why it is thoroughly studied to make it clear how it can be used safely for humans.
Another study indicates that epithalon facilitates the expression of differentiation and neurogenesis genes by binding to histone proteins H1\6 and H1\3 in human stem cells.
Epithalon is mostly known for its ability to influence the activity of the enzyme telomerase in somatic cells.
Telomeres are present at the end of chromosomes, which get shorter after every cell division, and if they become very short after division, they reach biological ageing or even die.
Epithalon enhances the expression of a certain gene, which adds nucleotide sequences at the end of chromosomes, which is hTERT ( human telomerase reverse transcriptase), and this works by increasing the activity of the telomerase enzyme.
Epithalon increases human cells’ lifespan and multiplying capacity by allowing human cells that are fibroblasts to multiply more than their Hayflick limit.
Study focus: Telomerase activation and telomere lengthening
Key findings: Studies suggest Epithalon may increase telomerase activity
Study focus: Long-term Epithalon administration in rodents
Key findings: Investigated for increasing lifespan and improved biomarkers of ageing
Study focus: Melatonin production and circadian regulation
Key findings: Investigated for its role in sleep and circadian rhythm regulation
Study focus: T-cell and NK cell activity in elderly subjects
Key findings: Studied for its potential effects on immune response
Study focus: Tumour suppression in mice
Key findings: Studied in tumour-related models
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