$127.00
IGF-1 LR3 is a synthetic, long-acting analog of insulin-like growth factor 1 (IGF-1), a naturally occurring growth factor involved in muscle repair, fat metabolism, cell regeneration, and anabolic growth. The LR3 version has been chemically modified for increased potency and a significantly extended half-life. It is commonly used for muscle development, anti-aging, and recovery.
85 in stock
IGF-1 LR3 is a modified form of Insulin-Like Growth Factor-1 (IGF-1). It has 83 amino acids, which makes it longer than the natural IGF-1 peptide and increases its stability in the human body.
The peptide has an arginine substitution at position 3 and has an additional 13-amino acid at the N-terminal end, which reduces the chance of its binding to IGF binding proteins and increases its biological activity.
It is a freeze-dried form, which is a white powder that is mixed with water before usage for research purposes
Recent research is ongoing on how IGF-1 LR3 affects muscle cell multiplication and its regeneration, which is a very interesting subject for muscle development and tissue repair research.
Scientists are curious about its role in promoting protein synthesis and cell growth by activating signaling pathways that regulate the tissue development processes, and this is the reason laboratory workers are now searching for IGF-1 LR3 for their research.
Some researchers are studying how IGF-1 LR3 can work by supporting faster recovery of damaged tissues, such as muscles or other tissues as well.
IGF-1 LR3 is mainly being studied because having the ability to bind the receptors of IGF-1 present in so many types of cells throughout the body.
When it binds to the receptor, it starts working by activating signaling pathways that are involved in cell growth and survival, such as PI3K/AKT and MAPK.
These pathways stimulate protein synthesis inside cells, which helps promote tissue growth and cellular repair processes.
Because of its structural modification, IGF-1 LR3 binds less strongly to IGF binding proteins, which allows it to remain active for a longer period as compared to natural IGF-1.
Findings: Promotes hypertrophy and muscle regeneration; activates satellite cells
Findings: Low IGF-1 linked to muscle loss; supplementation may help prevent sarcopenia
Findings: Improves brain plasticity and neuronal survival in models of neurodegeneration
Findings: Enhances bone mineralization and osteoblast function
Findings: Increases glucose uptake and improves insulin sensitivity
Findings: Extended half-life and reduced IGFBP binding increase anabolic effects
Summary Article: IGF-1 and its analogs: potential for treating muscle wasting
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