$179.00
SS-31 peptide is a mitochondria-targeted synthetic peptide from the Szeto-Schiller (SS) family, designed to protect and restore mitochondrial function. It selectively accumulates in the inner mitochondrial membrane (IMM), stabilizes cardiolipin, reduces oxidative stress, and enhances ATP production. SS-31 has been widely studied for its therapeutic potential in neurodegenerative, cardiovascular, metabolic, and renal conditions in which mitochondrial dysfunction is a core feature.
25 in stock
SS-31 Peptide protects you from acute kidney injury that is caused by cisplatin, ischemia and contrast agents. It reduces apoptosis, inflammation and necrosis.
Researchers have explored its potential in reverse age-related diastolic dysfunction. In aged mice, 8-week treatment has been shown to reverse cardiac hypertrophy and improve performance.
It can cross the blood-brain barrier and treat conditions like traumatic brain injury, subarachnoid haemorrhage, Alzheimer’s disease and neuroinflammation.
SS-31 (25mg) has been investigated for sarcopenia and muscle atrophy caused by disuse. It has shown its success in increasing tolerance and reversing mitochondrial deficits.
SS31 carries approximately 3+ net charge and exhibits electrostatic and hydrophobic interactions. Because it selectively concentrates about 5000-fold within the inner mitochondrial membrane. As it binds with specifically cardioplipin, which is critical for cristae structure, electron transport chain and ATP.
When binding CL, SS- 31 peptide can prevent the CL peroxidation during stress, as it maintains the structural integrity and inhibits the mitochondrial swelling.
SS31 can prevent the interaction of the CL with the cytochromes as it inhibits the conversion and cytochrome C into peroxide that causes the peroxidation and subsequent mitochondrial damage.
Study focus: Cardiolipin binding and ATP production
Findings: Stabilized IMM structure, improved ETC function, enhanced ATP production
Study focus: ROS and cytokine levels in cardiac injury
Findings: Decreased oxidative stress and inflammatory markers
Study focus: Cognitive function in Alzheimer’s models
Findings: Reduced neuroinflammation, improved mitochondrial health and memory
Study focus: Heart failure with reduced ejection fraction (HFrEF)
Findings: Preserved cardiac output and mitochondrial respiration
Study focus: Muscle fatigue and mitochondrial performance
Findings: Improved endurance, mitochondrial output, and insulin sensitivity
Study focus: Ischemia and oxidative injury in the kidneys
Findings: Reduced kidney damage, preserved mitochondrial integrity
The research centres can directly order it from the SunGod Lab’s platform. Bulk orders, handling instructions, or batch verification reports are also available upon request to facilitate seamless integration into laboratory workflows.
Note : Please review and adhere to our Terms and Conditions before ordering
Sequence:D-Arg-2′,6′-dimethyltyrosine-Lys-Phe-NH₂
Molecular Formula:C₃₀H₅₀N₈O₇
Molecular Weight:639.77 g/mol
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