ARA-290 (16mg)

$110.00

ARA 290 is a non-erythropoietic peptide that offers neuroprotection, pain relief, anti-inflammation, and tissue repair, especially for neuropathy.

25 in stock

Components of the ARA 290 (16mg)

The only component in ARA 290 is a non-linear with an 11-amino acid peptide, as referred to by PHBSP, Cibinetide, and Helix surface peptide.

Current Research Focus Of ARA 290 (16mg)

ARA 290 for Neuropathic Pain and Small Fibre Loss:

ARA 290 peptide is investigated for neuropathic pain associated with type 2 diabetes, sarcoidosis, and small nerve fibre loss.

ARA 290 for Anti-inflammatory and Tissue Repair:

Studies focus on the ARA 290 peptide for its ability to reduce inflammation and improve survival after myocardial infarction, and reduce organ dysfunction in haemorrhage models.

ARA 290 for Neuroprotection:

The research has suggested ARA 290 for its potential in diabetic retinopathy and mitigating the neuroinflammation by acting on the CNS.

Innate Repair Receptor (IRR) Activation:

It selectively binds with IRR, or ARA 290, as it triggers the tissue protective and anti-inflammatory signalling pathways for the production of red blood cells.

Anti-inflammatory Response:

It reduces the production of the pro-inflammatory cytokines like TNF, IL-1, and IL-6 in the context of injury and metabolic stress.

Suppression of Spinal Microglia:

In neuropathic pain, the ARA 290 suppresses the spinal microglia and the astrocyte as it reduces the neuroinflammation in the spinal cord.

Tissue Repair and Regeneration:

It promotes the fibre regrowth along with structural damage in diabetic neuropathy in small fibre neuropathy.

Diabetic Peripheral Neuropathy:

The research indicates that ARA 290 will improve neuropathic symptoms like pain, tingling and allodynia as it helps in metabolic control.

Stroke and Ischemic Injury:

The studies have shown that the mouse models in which the cerebral artery has been studied have shown that ARA 290 will reduce the brain infarction and neuronal apoptosis.

Immune System Modulation:

Studies focus on its effect on macrophages, decreasing pro-inflammatory cytokine production (e.g., TNF-α, IL-1β, IL-6).

Organ Damage Protection:

The research has shown protection against organ dysfunction in experimental models along with acute kidney injury.

References:

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Molecular Structure

Sequence (ARA-290 / Cibinetide): Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-OH

Molecular Formula: C₅₁H₈₄N₁₆O₂₁

Molecular Weight 1257.4 g/mol (free peptide)

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